MovDisordV3, Main, Exploration, bibRecord, 001219

Addenbrooke's Cognitive Examination-Revised for Mild Cognitive Impairment in Parkinson's Disease

Identifieur interne : 001219 ( Main/Exploration ); précédent : 001218; suivant : 001220

Addenbrooke's Cognitive Examination-Revised for Mild Cognitive Impairment in Parkinson's Disease

Auteurs : Peter Mccolgan [Royaume-Uni] ; Jonathan R. Evans [Royaume-Uni] ; David P. Breen [Royaume-Uni] ; Sarah L. Mason [Royaume-Uni] ; Roger A. Barker [Royaume-Uni] ; Caroline H. Williams-Gray [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2012.

RBID : Pascal:12-0339941

Descripteurs français

Pascal (Inist)
- Déficit cognitif léger, Trouble cognitif, Maladie de Parkinson, Démence, Pathologie du système nerveux, Sensibilité, Spécificité.

English descriptors

KwdEn :
- Cognitive disorder, Dementia, Nervous system diseases, Parkinson disease, Sensitivity, Specificity, mild cognitive impairment.

Abstract

Introduction: Cognitive impairment is common in Parkinson's disease (PD), even in the early stages, and appropriate screening tools are needed. Methods: We investigated the utility of the Addenbrooke's Cognitive Examination-Revised for detecting mild cognitive impairment (MCI) in PD in an incident population-representative cohort (n = 132) and investigated the relationship between performance on this instrument and behavior and quality of life (n = 219). Results: Twenty-two percent met criteria for MCI. Receiver operating curve analysis revealed an area under the curve of 0.81. A cutoff <89 gave a sensitivity of 69% and specificity of 84%. Scores on this instrument were highly correlated with the Parkinson's Disease Cognitive Rating Scale, and there were significant correlations with the Cambridge Behavioral Inventory-Revised and Parkinson's Disease Questionnaire 39. Conclusion: This instrument is a useful screening tool for PD-MCI, and poor performance is significantly related to impaired behavior and quality of life.

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Introduction: Cognitive impairment is common in Parkinson's disease (PD), even in the early stages, and appropriate screening tools are needed. Methods: We investigated the utility of the Addenbrooke's Cognitive Examination-Revised for detecting mild cognitive impairment (MCI) in PD in an incident population-representative cohort (n = 132) and investigated the relationship between performance on this instrument and behavior and quality of life (n = 219). Results: Twenty-two percent met criteria for MCI. Receiver operating curve analysis revealed an area under the curve of 0.81. A cutoff <89 gave a sensitivity of 69% and specificity of 84%. Scores on this instrument were highly correlated with the Parkinson's Disease Cognitive Rating Scale, and there were significant correlations with the Cambridge Behavioral Inventory-Revised and Parkinson's Disease Questionnaire 39. Conclusion: This instrument is a useful screening tool for PD-MCI, and poor performance is significantly related to impaired behavior and quality of life.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Addenbrooke's Cognitive Examination-Revised for Mild Cognitive Impairment in Parkinson's Disease

Addenbrooke's Cognitive Examination-Revised for Mild Cognitive Impairment in Parkinson's Disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri